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Symbol
Name
ID

Ace
angiotensin I converting enzyme
MGI:87874

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes

Increased circulating IgA level

Increased circulating IgG level

Decreased circulating antibody level

Paraproteinemia

Eosinophilia

Neutrophilia

Increased T cell count

Leukocytosis

Leukopenia

Keratoconjunctivitis sicca

Pericarditis

Abnormal lymph node morphology

Lymphadenopathy

Splenomegaly

Hepatosplenomegaly

Crohn's disease

Helicobacter pylori infection

Peritonitis

Subacute progressive viral hepatitis

Pancreatitis

Uveitis

Iridocyclitis

Epididymitis

Nephritis

Erysipelas

Erythema nodosum

Skin rash

Maculopapular exanthema

Autoimmunity

Asthma

Infectious encephalitis

Meningitis

Disease(s) Associated with ACE

asthma

Behcet's disease

familial mediterranean fever

hepatocellular carcinoma

IgA glomerulonephritis

multiple myeloma

pre-eclampsia

sarcoidosis

subacute sclerosing panencephalitis

type 1 diabetes mellitus

Mouse Phenotypes		increased basophil cell number	kidney inflammation	tubulointerstitial nephritis
Availability	Mouse Genotype	increased basophil cell number	kidney inflammation	tubulointerstitial nephritis
	Ace^tm1Keb/Ace^tm1Keb
	Ace^tm1Mcf/Ace^tm1Mcf
	Ace^tm1Unc/Ace^tm1Unc
	Ace^tm9Keb/Ace^tm9Keb
	Ace^{tm1.1(KOMP)Vlcg}/Ace⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23